
Where longevity meets medical support
L-Nutra Health is the medical division of L-Nutra, Prolon’s parent company. While Prolon supports overall health and healthy aging, L-Nutra Health focuses on chronic conditions like diabetes, obesity, prediabetes, and insulin resistance. Under medical supervision, L-Nutra Health leverages cutting-edge fasting and nutrition science to transform metabolic health management through a low-glycemic patented FMD, personalized nutrition therapy, and comprehensive health tracking - with medically-backed programs designed to improve metabolic health and reduce medication dependence without drastic lifestyle changes.
How it works ProgramsBy targeting root causes, remission - and even reversal - is possible
1-Cycle Trial or Maintenance

1 Cycle of Prolon can be used as a trial for the 3 or 4 cycle programs, and can be used for a quarterly maintenance program.
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Five Days to Cellular Rejuvenation
A physical and mental reset backed by 25 years of clinical research and science to rejuvenate at the cellular level.
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Lose Fat and Protect Muscle
Fat-targeted weight loss while preserving muscle – results shown to be sustainable even after returning to regular eating.
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Science-Backed Fasting Made Easier
Experience the benefits of fasting while still receiving nourishment, the revolution of fasting with food.
6 payments of $*.
Spread your cost over 6 months with APRs from 0%-24.99%. Get an instant decision with no impact on your credit.
Pay every month
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Payment of every month $*APRs from 0%-24.99%
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Make the most of your budgetAutomatic payments every month keep things flexible.
*Based on 0% APR, only available to qualified customers with excellent credit history and
subject to credit approval. A down payment may be required.
Actual APR based on creditworthiness and subject to credit approval, resulting in, for
example, 6 monthly payments of $166.67 to $179.02 per $1000 borrowed.
Minimum purchase of $149.
ProLon Reset.
ProLon ReSet is the only scientifically backed 1-day nutrition kit that puts your body in a fasting state, helping you take the time to reset and recharge.
It is also the perfect companion if you want to transition to an easier Intermittent Fasting experience during which you eat carb-controlled food and recoup some of the benefits of fasting!
Pay now or later - It's up to you.
Choose Shop Pay at checkout to pay in full or split your purchase into 4 equal installments of $18.75 *.
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No hidden feesNo interest, no fees, and no impact to your credit score.
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Make the most of your budgetAutomatic payments every two weeks keep things flexible.
*Subject to eligibility check and approval. Estimated payment amount excludes taxes and shipping fees. Notice to California Residents
Returning Patients
Prolon 5-Day (Fasting Mimicking Diet) Program
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With ProLon, you get everything you need pre-packaged and ready to go. Each kit comes with five boxes which are labeled by day so you know what to eat each day.
Soups
A variety of easy-to-prepare soups made with a proprietary mix of all-natural, plant-based ingredientsSoups
Nut Bars
Cold-pressed, delicious nut bars with whole ingredients like almonds, macadamia nuts, and pecansNut Bars
Snacks
Snacks like olives from the South of Spain where olive consumption is associated with longevity, and kale crackers enriched with plant-based protein.Snacks
Supplements
Dietary supplement packed with multivitamins, amino-acids, minerals and omega-3 fatty acid to provide the body with nourishmentSupplements
L-Drink
Fruit-flavored, proprietary glycerol mix designed to fuel and protect muscles throughout the fastL-Drink
Herbal Teas
Caffeine-free herbal teas loaded with healthy antioxidants, and will keep you hydrated during your week.Herbal Teas
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Prolon, essential to vibrant life!
Everyday we stress and intoxicate our body and mind with our current lifestyle, nutrition, environment we live under. As we age, our cellular capability to detox, recover and heal decrease and older senescent cells outnumber young vibrant cells.
Our ancestors had a natural secret to defend against accelerated aging and to rejuvenate younger cells: proLonged fasting (> 3 days). When fasting, the body uses its reserves (fat and glycogen) for the first 2 days (Intermittent Fasting period) but when fasting crosses 3 days or more (the prolonged fasting period), the body undergoes a next level of ‘protective and rejuvenative defense called autophagy.
In modern days, we accelerate cellular damage and aging vs going into periods of autophagy, recovery and rejuvenation.In 5 short days ProLon allows your body to go into a rejuvenating state, while consuming macro and micro nutrients to keep your body nourished.Healthy Aging
Metabolic Support
Mental Clarity
Changed Relationship with Food
Cellular Rejuvenation
Protect Lean Muscle
Rejuvenated Skin
More Energy
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4.4Rated 4.4 out of 5 starsBased on 6,119 reviews5Rated out of 5 stars4.2kTotal 5 star reviews: 4.2k4Rated out of 5 stars853Total 4 star reviews: 8533Rated out of 5 stars461Total 3 star reviews: 4612Rated out of 5 stars242Total 2 star reviews: 2421Rated out of 5 stars348Total 1 star reviews: 3486,119 reviews
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Melissa T.Verified BuyerI recommend this product2 months agoWill do this again!
It took 4 days but it worked!
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MaryBeth Z.Verified BuyerI recommend this product2 months agoGreat stuff!
Since I have been doing IF, getting thru this was not bad. Did not suffer from headaches or great hunger.
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roxanne y.Verified BuyerI recommend this product2 months agolove the support!
I love the support that is given with the proton fast
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Brianna C.Verified BuyerI recommend this product2 months agoHonest Review
I’ll be honest, the only soup I truly liked was the green pea and chive soup, the rest were kinda bad. I did finish the entire 5 days and that’s when I really felt the results of the FDM diet, I lost a total of 7 lbs which felt amazing but I was able to break some of my bad food habits (which I didn’t think was possible after 5 days!) but my vices were sugar and snacks. I always had to have a little bit of chocolate after lunch and dinner, I don’t have the craving anymore and I was snacking too much. Now I’m more mindful of what I am eating and when and the fast made me realize that hunger pains are not bad, I can ignore them and not immediately reach for food, I won’t die or start binging if I don’t eat. I’m excited to see where these new revelations take me and already thinking ahead to my fast. I also found that I have a ton of energy after the fast, which I wasn’t expecting. Overall it was a positive experience, I mean it was hard and some of the food wasn’t great but it was so easy because I knew what I could eat that day and it was worth it in the end.
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Emelina E.Verified BuyerI recommend this product2 months agoProlon changed me
My attitude towards foods changed, my habits and routine changed, too, I feel like a new person, I’ll do it again to maintain my well being
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Backed by & continually advancing through science.
After two decades and tens of millions in Research & Development, L-Nutra (a leading Nutri-tech company) and The University of Southern California, led by Dr. Valter Longo were able to identify cellular radars that detect nutrition, called Nutrient Sensing Pathways, and to develop a 5 day Nutrition Program that nourishes the body while the food sensing pathways are not triggered and therefore providing the prolonged fasting benefits.
Prolon provides the body with healthy, plant-based ingredients that have been scientifically demonstrated to provide the body with optimal nourishment while not activating the key pro-aging pathways, or food sensing pathways — pathways which are activated by normal diets.
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SoupsSnacksDrinksSupplements
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Prolon is eligible for purchase and reimbursement with HSA/FSA — partnered with TrueMed.
Programs like health savings accounts (HSA) and flexible spending accounts (FSA) enable individuals to allocate pre-tax money for qualified healthcare expenses. Prolon has partnered with TrueMed, allowing customers to use their HSA/FSA funds to purchase our science backed products. -
How many times do I do Prolon each year?
The amazing part about ProLon is it can easily fit into your lifestylle and is only a 5 day change to your normal life.
Suggested consumption by Dr. Valter Longo, head of the Longevity Institute at University of Southern California and Author of the Longevity Diet.
• If you have a health or metabolic objective in mind and want to achieve faster the metabolic and rejuvenative successes of ProLon, then you can do ProLon every month for 3 or 4 months and then do it once every 3 months to maintain the benefits.
• 2 times only per year for Healthy Aging (10 days out of 365 days!)
• 3 times per year for Healthy Aging and added Weight Loss (15 days out of 365 days!)
Some people do ProLon once a month for reasons that are in line with therapeutic effects of fasting that we are also researching and will launch under a dietitian guided program in 2023.
How should the Prolon program be used?
The diet should be used for five consecutive days, after which the individual will transition on the 6th day and then resume their normal diet. The program provides a meal card that recommends how to consume the items for each day, but each day’s items can be consumed in any order you wish, as long as you only eat each day’s items during that day (do not carry them over to the next).
What are the food pathways affected by Prolon?
While there are many different signaling factors in the “nutrient-sensing pathways” involved with cellular fasting, the 3 primary nutrient-sensing pathways that ProLon and fasting down-regulate are IGF-1, mTOR, and PKA. The process is complex, and each pathway can interact with other pathways, but in general, PKA responds primarily to sugar and carbohydrates, while IGF-1 is primarily responsive to protein (and more strongly triggered by animal protein), and mTOR is triggered by IGF-1 and amino acids. Sugar and carbohydrates (and to some extent caffeine) will activate PKA. These nutrient-sensing pathways all help regulate the cells’ growth cycles and stress-resistant “fasting” state.
What happens to my body during the fasting mimicking program?
ProLon provides the body with a scientifically developed, naturally occurring combination of macronutrients (fats, carbohydrates, proteins) and micronutrients (essential vitamins and minerals) designed to keep the body nourished while going through the rejuvenating process of the fasting state.
WHAT HAPPENS ON DAYS 1 TO 5 ON MY PROLON FAST?
Day 1: Transforming to a Fasting State: Your body is transitioning to a fasting state and fat- burning mode, and begins preparation for cellular clean-up.
Day 2: Fat Burning & Ketogenesis: Fast Burning & Ketogenesis: Fat-Burning ramps up, contributing to the initiation of ketogenesis (ketone production). By the end of this day (48 hours), ketosis may occur.
Day 3: Autophagy Clean Up State: Cellular clean-up (autophagy) Fat-burning and ketone production/utilization continues and increases.
Day 4: Cellular Rejuvenation:Cellular cleaning/renewal & fat-burning You’re in the final stretch.
Day 5: Renewal & Change: Fast completed, cellular renewal continues beyond Day 5.
How much weight am I expect to lose?
While the purpose of the ProLon diet is to trigger rejuvenation, weight loss may occur. Everyone is different, and weight loss depends on a number of factors. In a clinical study of participants who completed a 5-day ProLon cycle once a month for three months, the average weight loss at the end of the study was about 5.7 pounds. This was primarily abdominal fat, while lean body mass was preserved.
What is the daily caloric intake during Prolon?
Day 1 has about 1100 calories (kcals), while Days 2-5 have between 700 and 800 calories (kcals) per day.
How it works
L-Nutra Health programs go beyond symptom management by addressing the underlying causes of metabolic conditions—such as muscle loss, abdominal fat, and cellular aging. Through clinically validated, dietitian-guided comprehensive programs centered around cycles of a low-glycemic FMD, L-Nutra Health programs offer a proactive solution for prevention, management, remission, and even reversal. Learn more
When used as part of a comprehensive program, the FMD has shown:
- 59% reduction in insulin resistance (1)
- 22 lbs average fat-focused weight loss while preserving muscle (1)
- 1.4% decrease in A1c levels (1)
- 67% reduction or elimination of medication reliance (1)
- Estimated savings of $41,613 for patients on two or more medications after following a 3-year FMD program (2)
- Reduction in biological age score and improved cardiometabolic markers (3)

What programs do they offer?
L-Nutra Health’s structured, clinically-validated, comprehensive programs are designed to improve and potentially reverse metabolic health conditions without drastic lifestyle changes and reduce medication dependence. They provide:


360-degree on going support from trained professionals
Low-glycemic 5-Day Fasting Mimicking Diet (FMD) to stabilize glucose levels
12-Month Diabetes Remission Program
A twelve-month program that includes medical oversight, medication and lab monitoring, and multiple FMD cycles personalized to specific need
Six-Month Metabolic Health Program
A six-month program that includes four FMD cycles paired with Longevity Diet principles to meet your personalized needs

Promete 5-Day Trial Program
A five day, introductory plan to experience a 5-day FMD that is health coach-guided before committing to a long-term program
Prolon or L-Nutra Health: Which is right for you?
L-Nutra Health programs and Prolon 5-Day cater to different wellness needs. For detailed guidance on how to decide which program is right for you, click here.
1. L-Nutra Health Programs
For those with metabolic conditions like prediabetes, type 2 diabetes, insulin resistance, and obesity, these comprehensive, medically guided programs aim to improve or even reverse metabolic health conditions and reduce or eliminate medication reliance.

2. Prolon 5-Day
A 5-day self-guided fasting-mimicking cycle for generally healthy individuals focused on longevity, wellness, and weight care. This convenient, research-backed intervention promotes cellular rejuvenation, fat-focused weight loss, and healthy aging. It is recommended to start with three consecutive monthly cycles, followed by three to four cycles yearly.

1. When used as part of a comprehensive program over six months: https://academic.oup.com/jcem/article/107/8/2167/6576281
2. As predicted in part of a 10-year modeling evaluation: https://www.valueinhealthjournal.com/article/S1098-3015(24)02846-8/fulltext
3. After three consecutively monthly cycles:
https://www.nature.com/articles/s41467-024-45260-9